Somatostatin 3 mg, powder for solution for infusion

Somatostatin, also known as growth hormone-inhibiting hormone is a 14-amino acid oligopeptide which was originally isolated from the hypothalamus of animals and, later, found in both epithelial cells and nerve fibers throughout the whole of the digestive system. Somatostatin is thought to act mainly as a local transport substance, thus having a role in both the regulation of endocrine and exocrine secretions and of gastrointestinal motility. When administered at pharmacological doses, somatostatin will inhibit gastrointestinal function and motility, as well as resorption within the digestive tract.

It is used to treat the acute gastrointestinal hemorrhage, resulting from gastric or duodenal ulcers, hemorrhagic gastritis and bleeding esophageal varices, whether suspected solely on clinical grounds or proven by endoscopy.
Treatment of intestinal and pancreatic fistulae.
Symptomatic treatment of excessive secretion from endocrine tumors of the gastrointestinal tract.
The prevention of complications after pancreatic surgery or endoscopic retrograde cholangiopancreatography (ERCP).