Esomeprazole 40 mg lyophilized powder for solution for injection/infusion

Esomeprazole for injection and infusion is indicated for:

• Gastric antisecretory treatment when the oral route is not possible, such as:

• gastroesophageal reflux disease (GERD) in patients with esophagitis and/or severe symptoms of reflux.

• healing of gastric ulcers associated with NSAID therapy.

• prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk.

• Prevention of rebleeding following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers.

Esomeprazole is the S-isomer of omeprazole and reduces gastric acid secretion through a specific targeted mechanism of action. It is a specific inhibitor of the acid pump in the parietal cell. Both the R- and S-isomer of omeprazole have similar pharmacodynamic activity.