Brimonidine
code: S01EA05
Brimonidine Rompharm (brimonidine tartrate ) 2 mg/mL eye drops, solution
Therapeutic indications
Reduction of elevated intraocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension.
Brimonidine is an alpha-2 adrenergic receptor.
Topical administration of brimonidine tartrate 0.2% solution decreases intraocular pressure (IOP) in humans by mean values of approximately 10-12 mmHg, with peak ocular hypotensive effect seen at two hours.
Brimonidine tartrate has a dual mechanism of action. It is thought that brimonidine may lower IOP by reducing aqueous humour formation and enhancing uveoscleral outflow.